DUSP5 anticorps (Middle Region)

N° du produit ABIN2787599

Détail du produit anti-DUSP5 anticorps

Antigène: DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Chien, Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP5 est non-conjugé

Application: Western Blotting (WB)

Séquence: AGSSLIGHLQ TLSPDMQGAY CTFPASVLAP VPTHSTVSEL SRSPVATATS

Homologie: Cow: 85%, Dog: 92%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 86%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against DUSP5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human DUSP5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 384 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DUSP5

Antigène: DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))

Autre désignation: DUSP5 (DUSP5 Produits)

Synonymes: anticorps DUSP5, anticorps wu:fc03b11, anticorps wu:fc86e02, anticorps MGC84792, anticorps dusp, anticorps hvh3, anticorps DUSP, anticorps HVH3, anticorps Cpg21, anticorps Gm337, anticorps dual specificity phosphatase 5, anticorps dual specificity phosphatase 5 S homeolog, anticorps DUSP5, anticorps dusp5, anticorps dusp5.S, anticorps Dusp5

Sujet: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
Alias Symbols: DUSP, HVH3
Protein Interaction Partner: ELAVL1, UBC, MAPK3, MAPK1,
Protein Size: 384

Poids moléculaire: 42 kDa

ID gène: 1847

NCBI Accession: NM_004419, NP_004410

UniProt: Q16690