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POT1 anticorps (Middle Region)

POT1 Reactivité: Humain, Souris, Rat, Cobaye, Chien, Cheval, Boeuf (Vache), Porc, Lapin, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2787632
  • Antigène Voir toutes POT1 Anticorps
    POT1 (Protection of Telomeres 1 (POT1))
    Épitope
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    Humain, Souris, Rat, Cobaye, Chien, Cheval, Boeuf (Vache), Porc, Lapin, Poisson zèbre (Danio rerio)
    Hôte
    • 21
    • 1
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp POT1 est non-conjugé
    Application
    • 11
    • 9
    • 2
    • 2
    Western Blotting (WB)
    Séquence
    MNSENQTMLS LEFHLHGGTS YGRGIRVLPE SNSDVDQLKK DLESANLTAN
    Homologie
    Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against POT1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human POT1
    Top Product
    Discover our top product POT1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 634 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    POT1 (Protection of Telomeres 1 (POT1))
    Autre désignation
    POT1 (POT1 Produits)
    Synonymes
    anticorps HPOT1, anticorps POT1, anticorps DKFZp469P1825, anticorps pot1, anticorps 1500031H18Rik, anticorps AI851169, anticorps Pot1, anticorps Pot1a, anticorps protection of telomeres 1, anticorps protection of telomeres 1 L homeolog, anticorps protection of telomeres 1A, anticorps POT1, anticorps pot1.L, anticorps Pot1a, anticorps Pot1
    Sujet
    This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
    Alias Symbols: DKFZP586D211, hPot1, HPOT1
    Protein Interaction Partner: TPP1, CFL2, ACD, CORO1A, KHDRBS1, LAMC3, BCAS2, MVP, ZNF32, ECI1, CSNK2B, COX6A2, ALDH1A1, ACTN4, SERTAD1, C2orf74, ZBTB49, ZBED2, CYP4F11, MYO5C, RIF1, NAP1L1, MDM2, KRT18, GRN, PACSIN1, SULT4A1, PGLS, AIPL1, SH3BP1, HAAO, NCDN, TWF2, ACOT7, DDX19B, PACS
    Protein Size: 634
    Poids moléculaire
    70 kDa
    ID gène
    25913
    NCBI Accession
    NM_015450, NP_056265
    UniProt
    Q9NUX5
    Pathways
    Cycle Cellulaire, Telomere Maintenance
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