CAPZA3 anticorps (N-Term)

N° du produit ABIN2787761

Détail du produit anti-CAPZA3 anticorps

Antigène: CAPZA3 (Capping Protein (Actin Filament) Muscle Z-Line, alpha 3 (CAPZA3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAPZA3 est non-conjugé

Application: Western Blotting (WB)

Séquence: MTLSVLSRKD KERVIRRLLL QAPPGEFVNA FDDLCLLIRD EKLMHHQGEC

Homologie: Dog: 92%, Guinea Pig: 92%, Human: 100%, Mouse: 85%, Rabbit: 92%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against CAPZA3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CAPZA3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 299 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CAPZA3

Antigène: CAPZA3 (Capping Protein (Actin Filament) Muscle Z-Line, alpha 3 (CAPZA3))

Autre désignation: CAPZA3 (CAPZA3 Produits)

Synonymes: anticorps CAPZA3, anticorps CAPPA3, anticorps Gsg3, anticorps 510-4, anticorps Cappa3, anticorps Tex8, anticorps repro32, anticorps capping actin protein of muscle Z-line alpha subunit 3, anticorps capping protein (actin filament) muscle Z-line, alpha 3, anticorps CAPZA3, anticorps Capza3

Sujet: F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. CAPZA3 may play a role in the morphogenesis of spermatid.This gene encodes an actin capping protein, one of the F-actin capping protein alpha subunit family. The encoded protein is predominantly localized to the neck region of ejaculated sperm, other immunohistochemical signals were found in the tail and postacrosomal regions. The encoded protein may also form heterodimers of alpha and beta subunits. This protein may be important in determining sperm architecture and male fertility.
Alias Symbols: CAPPA3, Gsg3
Protein Interaction Partner: UBC, CAPZA2, ACTG1,
Protein Size: 299

Poids moléculaire: 33 kDa

ID gène: 93661

NCBI Accession: NM_033328, NP_201585

UniProt: Q96KX2

Pathways: Regulation of Actin Filament Polymerization