alpha KGDHC anticorps (N-Term)

N° du produit ABIN2787780

Détail du produit anti-alpha KGDHC anticorps

Antigène: alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp alpha KGDHC est non-conjugé

Application: Western Blotting (WB)

Séquence: MFHLRTCAAK LRPLTASQTV KTFSQNRPAA ARTFQQIRCY SAPVAAEPFL

Homologie: Cow: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against OGDH. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human OGDH

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 427 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur alpha KGDHC

Antigène: alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))

Autre désignation: OGDH (alphaKGDHC Produits)

Synonymes: anticorps AKGDH, anticorps E1k, anticorps OGDC, anticorps 2210403E04Rik, anticorps 2210412K19Rik, anticorps AA409584, anticorps d1401, anticorps mKIAA4192, anticorps oxoglutarate dehydrogenase, anticorps oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide), anticorps OGDH, anticorps Ogdh

Sujet: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitocondrial matrix and uses thiamine pyrophosphate as a cofactor. A congential deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia.
Alias Symbols: AKGDH, E1k, OGDC
Protein Interaction Partner: MDM2, UBC, SUMO1, NEDD8, CPSF7, MRPL38, MRPL41, TSR1, MRPS2, MRPL15, MRPL13, SCFD1, PDHX, SSBP1, SUMO2, PDHB, PDHA1, DLST, DLAT, DHODH, ISG15, USP13, PLSCR1, DLD,
Protein Size: 427

Poids moléculaire: 47 kDa

ID gène: 4967

NCBI Accession: NM_001003941, NP_001003941

UniProt: Q96DD3