USP10 anticorps (C-Term)
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- Antigène Voir toutes USP10 Anticorps
- USP10 (Ubiquitin Specific Peptidase 10 (USP10))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp USP10 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- RDIRPGAAFE PTYIYRLLTV IKSSLSEKGR QEDAEEYLGF ILNGLHEEML
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against Usp10. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product USP10 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 794 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- USP10 (Ubiquitin Specific Peptidase 10 (USP10))
- Autre désignation
- Usp10 (USP10 Produits)
- Synonymes
- anticorps T4F9.30, anticorps T4F9_30, anticorps ubiquitin-specific protease 9, anticorps ubpo, anticorps USP10, anticorps id:ibd1190, anticorps wu:fc19h08, anticorps wu:fc76g05, anticorps wu:fi11g01, anticorps UBPO, anticorps 2610014N07Rik, anticorps Uchrp, anticorps mKIAA0190, anticorps usp10-A, anticorps ubiquitin specific peptidase 10, anticorps universal stress protein UspA, anticorps ubiquitin-specific protease 9, anticorps ubiquitin carboxyl-terminal hydrolase 10, anticorps ubiquitin specific peptidase 10 S homeolog, anticorps USP10, anticorps RR_RS14970, anticorps UBP9, anticorps PTRG_07201, anticorps MGYG_06403, anticorps usp10, anticorps Usp10, anticorps usp10.S
- Sujet
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Usp10 is a hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. It acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53. Following DNA damage, translocates to the nucleus and deubiquitinates p53/TP53, leading to regulate the p53/TP53-dependent DNA damage response. Usp10 does not deubiquitinate MDM2 and deubiquitinates CFTR in early endosomes, enhancing its endocytic recycling.
Alias Symbols: MGC124997
Protein Size: 794 - Poids moléculaire
- 87 kDa
- ID gène
- 307905
- NCBI Accession
- NM_001034146, NP_001029318
- UniProt
- Q3KR59
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