GRM7 anticorps (C-Term)
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- Antigène Voir toutes GRM7 Anticorps
- GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
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Épitope
- C-Term
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Reactivité
- Humain, Rat, Souris, Chien, Lapin, Boeuf (Vache), Cheval, Poisson zèbre (Danio rerio), Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GRM7 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- HPELNVQKRK RSFKAVVTAA TMSSRLSHKP SDRPNGEAKT ELCENVDPNS
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against GRM7. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human GRM7
- Top Product
- Discover our top product GRM7 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 915 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
- Autre désignation
- GRM7 (GRM7 Produits)
- Synonymes
- anticorps MGLUR7, anticorps GLUR7, anticorps GPRC1G, anticorps MGLU7, anticorps 6330570A01Rik, anticorps BB176677, anticorps C030018L03, anticorps E130018M02Rik, anticorps Gpr1g, anticorps Gprc1g, anticorps mGluR7, anticorps glutamate metabotropic receptor 7, anticorps glutamate receptor, metabotropic 7, anticorps GRM7, anticorps Grm7
- Sujet
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L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ40498, GLUR7, GPRC1G, MGLU7, MGLUR7
Protein Interaction Partner: UBC, PICK1, TUBA8, TUBA1B, TUBA1A, TUBA3C, GNAQ, GRIPAP1, FLNA, TUBA4A, CALM3, CALM1, PRKCA, GRIP1, SDCBP,
Protein Size: 915 - Poids moléculaire
- 99 kDa
- ID gène
- 2917
- NCBI Accession
- NM_000844, NP_000835
- UniProt
- Q14831
- Pathways
- Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour
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