RNLS anticorps (Middle Region)
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- Antigène Voir toutes RNLS Anticorps
- RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))
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Épitope
- Middle Region
- Reactivité
- Humain, Souris, Rat, Cheval, Porc, Lapin, Chien, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RNLS est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- GMKIGVPWSC RYLSSHPCIC FISIDNKKRN IESSECGPSV VIQTTVPFGV
- Homologie
- Dog: 79%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against Rnls. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product RNLS Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 300 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))
- Autre désignation
- Rnls (RNLS Produits)
- Sujet
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Rnls is a probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. It degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. It lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.
Alias Symbols: 6530404N21Rik, AI452315, AW060440, C10orf59
Protein Size: 300 - Poids moléculaire
- 33 kDa
- ID gène
- 67795
- NCBI Accession
- NM_001167818, NP_001161290
- UniProt
- A7RDN6
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