SPR anticorps (C-Term)
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- Antigène Voir toutes SPR Anticorps
- SPR (Sepiapterin Reductase (SPR))
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Épitope
- C-Term
- Reactivité
- Humain, Souris, Rat, Chien, Cheval, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SPR est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- ETSVDPDMRK GLQELKAKGK LVDCKVSAQK LLSLLEKDEF KSGAHVDFYD
- Homologie
- Dog: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against SPR. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human SPR
- Top Product
- Discover our top product SPR Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 261 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- SPR (Sepiapterin Reductase (SPR))
- Autre désignation
- SPR (SPR Produits)
- Sujet
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This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
Alias Symbols: SDR38C1
Protein Interaction Partner: UBC, YWHAQ, MRPL53, SRPRB, SUGP1, SBDS, AHCYL1, SCO2, RAD23B, PPM1G, NDUFA2, IDH3G, CRK, ASS1, CAMK2G,
Protein Size: 261 - Poids moléculaire
- 28 kDa
- ID gène
- 6697
- NCBI Accession
- NM_003124, NP_003115
- UniProt
- P35270
- Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
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