SPR anticorps (C-Term)

N° du produit ABIN2788144

Détail du produit anti-SPR anticorps

Antigène: SPR (Sepiapterin Reductase (SPR))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPR est non-conjugé

Application: Western Blotting (WB)

Séquence: ETSVDPDMRK GLQELKAKGK LVDCKVSAQK LLSLLEKDEF KSGAHVDFYD

Homologie: Dog: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against SPR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human SPR

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 261 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SPR

Antigène: SPR (Sepiapterin Reductase (SPR))

Autre désignation: SPR (SPR Produits)

Sujet: This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
Alias Symbols: SDR38C1
Protein Interaction Partner: UBC, YWHAQ, MRPL53, SRPRB, SUGP1, SBDS, AHCYL1, SCO2, RAD23B, PPM1G, NDUFA2, IDH3G, CRK, ASS1, CAMK2G,
Protein Size: 261

Poids moléculaire: 28 kDa

ID gène: 6697

NCBI Accession: NM_003124, NP_003115

UniProt: P35270

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration