RASSF1 anticorps (C-Term)
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- Antigène Voir toutes RASSF1 Anticorps
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
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Épitope
- C-Term
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc, Chien, Mouton, Poisson zèbre (Danio rerio), Cobaye, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RASSF1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LAGPSDKALS FVLKENDSGE VNWDAFSMPE LHNFLRILQR EEEEHLRQIL
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 85%
- Attributs du produit
- This is a rabbit polyclonal antibody against RASSF1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human RASSF1
- Top Product
- Discover our top product RASSF1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 270 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
- Autre désignation
- RASSF1 (RASSF1 Produits)
- Synonymes
- anticorps RASSF1, anticorps zgc:92505, anticorps wu:fc17f02, anticorps zgc:112224, anticorps 123F2, anticorps NORE2A, anticorps RASSF1A, anticorps RDA32, anticorps REH3P21, anticorps AA536941, anticorps AU044980, anticorps Rassf1A, anticorps Rassf1B, anticorps Rassf1C, anticorps NPR2-like, GATOR1 complex subunit, anticorps Ras association (RalGDS/AF-6) domain family 1, anticorps Ras association domain family member 1, anticorps putative rassf1, anticorps Ras association domain family member 1 L homeolog, anticorps Ras association (RalGDS/AF-6) domain family member 1, anticorps NPRL2, anticorps rassf1, anticorps RASSF1, anticorps Smp_157340, anticorps rassf1.L, anticorps Rassf1
- Sujet
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This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Alias Symbols: 123F2, NORE2A, RASSF1A, RDA32, REH3P21
Protein Interaction Partner: FBXW11, MDM2, DAXX, SUV39H2, KDM1A, SUV39H1, STK4, STK3, CDC20, SAV1, MAST2, HUWE1, LATS1, BTRC, UBC, ID1, GSK3B, C7orf25, C8orf33, KCNE3, CUL4A, DDB1, Rassf1, SKP2, AURKB, AURKA, SKP1, CUL1, NUDT10, MOAP1, CNKSR1, MAP1S, EXOSC8, RASSF5, TNFRSF10A, E4F1,
Protein Size: 270 - Poids moléculaire
- 30 kDa
- ID gène
- 11186
- NCBI Accession
- NM_170713, NP_733831
- UniProt
- Q9NS23
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