CERKL anticorps (C-Term)

N° du produit ABIN2788232

Détail du produit anti-CERKL anticorps

Antigène: CERKL (Ceramide Kinase-Like (CERKL))

Épitope: C-Term

Reactivité: Humain, Souris, Lapin, Cheval, Chien, Cobaye, Rat, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CERKL est non-conjugé

Application: Western Blotting (WB)

Séquence: ASVKNQFNFP FVETYTVEEV KVHPRNNTGG YNPEEEEDET ASENCFPWNV

Homologie: Dog: 90%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 81%, Rat: 79%, Yeast: 89%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against CERKL. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CERKL

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 463 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CERKL

Antigène: CERKL (Ceramide Kinase-Like (CERKL))

Autre désignation: CERKL (CERKL Produits)

Synonymes: anticorps RGD1561057, anticorps Gm1958, anticorps Rp26, anticorps GB19002, anticorps RP26, anticorps zgc:162213, anticorps ceramide kinase like, anticorps ceramide kinase-like, anticorps ceramide kinase, anticorps CERKL, anticorps Cerkl, anticorps LOC408315, anticorps CERK, anticorps LOC100566923, anticorps LOC100645684, anticorps cerkl

Sujet: This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.
Alias Symbols: RP26
Protein Size: 463

Poids moléculaire: 51 kDa

ID gène: 375298

NCBI Accession: NM_001030313, NP_001025484

UniProt: Q49MI3