IGSF8 anticorps (Middle Region)
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- Antigène Voir toutes IGSF8 Anticorps
- IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Boeuf (Vache), Porc, Lapin, Chien, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IGSF8 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LAVEAGAPYA ERLAAGELRL GKEGTDRYRM VVGGAQAGDA GTYHCTAAEW
- Homologie
- Cow: 86%, Dog: 79%, Guinea Pig: 83%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against IGSF8. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human IGSF8
- Top Product
- Discover our top product IGSF8 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 613 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))
- Autre désignation
- IGSF8 (IGSF8 Produits)
- Sujet
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IGSF8 may play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. IGSF8 may also play a role on integrin-dependent morphology and motility functions. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.
Alias Symbols: CD316, CD81P3, EWI2, PGRL, EWI-2, KCT-4, LIR-D1
Protein Interaction Partner: KRTAP10-3, KRTAP10-8, KRTAP10-9, KRTAP10-7, KRTAP10-4, UBC, FBXO6, HIST1H2BK, TUBB6, TUBB7P, VPS35, TUBA8, EIF3L, TUBE1, RPL26L1, YBX2, EIF3K, LSM3, PDCD4, PABPC1, IBTK, RPL36, RPL13A, SF3B3, RPL35, SUPT16H, SRSF8, PRPF8, CCT4, ANP32B, DDX17, SYNCRIP, TUB
Protein Size: 613 - Poids moléculaire
- 65 kDa
- ID gène
- 93185
- NCBI Accession
- NM_052868, NP_443100
- UniProt
- Q969P0
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