MRGPRX2 anticorps (Middle Region)
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- Antigène Voir toutes MRGPRX2 Anticorps
- MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))
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Épitope
- Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MRGPRX2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- VCVLLWALSL LLSILEGKFC GFLFSDGDSG WCQTFDFITA AWLIFLFMVL
- Homologie
- Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against MRGPRX2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human MRGPRX2
- Top Product
- Discover our top product MRGPRX2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 330 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))
- Autre désignation
- MRGPRX2 (MRGPRX2 Produits)
- Synonymes
- anticorps MRGX2, anticorps G370024M05Rik, anticorps MrgB10, anticorps Mrgprb10, anticorps MrgB1, anticorps Mrgprb1, anticorps MAS related GPR family member X2, anticorps MAS-related GPR, member X2, anticorps MRGPRX2, anticorps Mrgprx2
- Sujet
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MRGPRX2 is an orphan receptor. It probably involved in the function of nociceptive neurons. It also may regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca2+ but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled.
Alias Symbols: MRGX2
Protein Interaction Partner: CORT,
Protein Size: 330 - Poids moléculaire
- 37 kDa
- ID gène
- 117194
- NCBI Accession
- NM_054030, NP_473371
- UniProt
- Q96LB1
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