Adenosine A3 Receptor anticorps (C-Term)

N° du produit ABIN2788278

Détail du produit anti-Adenosine A3 Receptor anticorps

Antigène: Adenosine A3 Receptor (ADORA3)

Épitope: C-Term

Reactivité: Humain, Porc, Boeuf (Vache), Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Adenosine A3 Receptor est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: RSCKAPKVVR KADRSRTSIL IICILITGLG IISVISHLTK RRRSQRNRRV

Homologie: Cow: 75%, Horse: 93%, Human: 100%, Pig: 85%, Rabbit: 77%

Attributs du produit: This is a rabbit polyclonal antibody against ADORA3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ADORA3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 266 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Adenosine A3 Receptor (ABIN2788278)

Merighi, Benini, Mirandola, Gessi, Varani, Leung, Maclennan, Baraldi, Borea: "Hypoxia inhibits paclitaxel-induced apoptosis through adenosine-mediated phosphorylation of bad in glioblastoma cells." dans: Molecular pharmacology, Vol. 72, Issue 1, pp. 162-72, (2007) (PubMed).

Détails sur Adenosine A3 Receptor

Antigène: Adenosine A3 Receptor (ADORA3)

Autre désignation: ADORA3 (ADORA3 Produits)

Synonymes: anticorps A3AR, anticorps AD026, anticorps bA552M11.5, anticorps ADORA3, anticorps 1700001D09Rik, anticorps 4930578J19Rik, anticorps A3R, anticorps AA3R, anticorps ARA3, anticorps Gpcr2, anticorps adenosine A3 receptor, anticorps adenosine receptor A3, anticorps ADORA3, anticorps Adora3, anticorps LOC100603318

Sujet: This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: A3AR, AD026, bA552M11.5, RP11-552M11.7
Protein Interaction Partner: YWHAQ, YWHAZ,
Protein Size: 266

Poids moléculaire: 30 kDa

ID gène: 140

NCBI Accession: NM_001081976, NP_001075445

UniProt: Q5QNY7

Pathways: Hormone Transport, cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process