F2RL1 anticorps (C-Term)

N° du produit ABIN2788314

Détail du produit anti-F2RL1 anticorps

Antigène: F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))

Épitope: C-Term

Reactivité: Humain, Rat, Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp F2RL1 est non-conjugé

Application: Western Blotting (WB)

Séquence: VSHDFRDHAK NALLCRSVRT VKQMQVSLTS KKHSRKSSSY SSSSTTVKTS

Homologie: Dog: 93%, Guinea Pig: 86%, Human: 100%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against F2RL1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 397 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-F2RL1 (ABIN2788314)

Yau, Liu, Fairlie: "Toward drugs for protease-activated receptor 2 (PAR2)." dans: Journal of medicinal chemistry, Vol. 56, Issue 19, pp. 7477-97, (2013) (PubMed).

Détails sur F2RL1

Antigène: F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))

Autre désignation: F2RL1 (F2RL1 Produits)

Sujet: Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83 % identical to the mouse receptor sequence.
Alias Symbols: GPR11, PAR2
Protein Interaction Partner: BIRC5, COPS5, UBC, Cbl, ST14, GPRASP1, PRTN3, F2, PLG, ELANE, CTSG, CAPN2, CAPN1,
Protein Size: 397

Poids moléculaire: 44 kDa

ID gène: 2150

NCBI Accession: NM_005242, NP_005233

UniProt: P55085

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome