MRPL49 anticorps (N-Term)

N° du produit ABIN2788326

Détail du produit anti-MRPL49 anticorps

Antigène: MRPL49 (Mitochondrial Ribosomal Protein L49 (MRPL49))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MRPL49 est non-conjugé

Application: Western Blotting (WB)

Séquence: ESVDEYQFVE RLLPATRIPD PPKHEHYPTP SGWQPPRDPP PNLPYFVRRS

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 79%, Rabbit: 83%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against MRPL49. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MRPL49

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 166 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MRPL49

Antigène: MRPL49 (Mitochondrial Ribosomal Protein L49 (MRPL49))

Autre désignation: MRPL49 (MRPL49 Produits)

Synonymes: anticorps Aa2-277, anticorps BcDNA:RE35556, anticorps CG4647, anticorps Dmel\\CG4647, anticorps MRP-L49, anticorps mRpl49, anticorps C11orf4, anticorps L49mt, anticorps NOF, anticorps NOF1, anticorps 4833419D18Rik, anticorps Nof1, anticorps mitochondrial ribosomal protein L49, anticorps Mrpl49, anticorps mRpL49, anticorps MRPL49

Sujet: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for the HRD1 protein use in their respective 3' UTRs some of the same genomic sequence. Pseudogenes corresponding to this gene are found on chromosomes 5q and 8p.
Alias Symbols: C11orf4, L49mt, MGC10656, NOF, NOF1, MRP-L49
Protein Interaction Partner: CEP57, NPM1, METTL18, MRPL52, PRKCDBP, TMEM177, MRPL38, MRPL39, NENF, TIMM10, SCFD1, PPT2, MTHFD1, MGST3, DLST, CDH2, APP, CAND1, COPS5, CUL1, CUL3, TCF3, UBC, ICT1, OXA1L,
Protein Size: 166

Poids moléculaire: 19 kDa

ID gène: 740

NCBI Accession: NM_004927, NP_004918

UniProt: Q13405