CTSC anticorps (Middle Region)
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- Antigène Voir toutes CTSC Anticorps
- CTSC (Cathepsin C (CTSC))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Boeuf (Vache), Chien, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CTSC est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- WTATTYMEYE TLTLGDMIRR SGGHSRKIPR PKPAPLTAEI QQKILHLPTS
- Homologie
- Cow: 86%, Dog: 79%, Horse: 86%, Human: 100%, Mouse: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against CTSC. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human CTSC
- Top Product
- Discover our top product CTSC Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 463 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- CTSC (Cathepsin C (CTSC))
- Autre désignation
- CTSC (CTSC Produits)
- Synonymes
- anticorps CPPI, anticorps DPP-I, anticorps DPP1, anticorps DPPI, anticorps HMS, anticorps JP, anticorps JPD, anticorps PALS, anticorps PDON1, anticorps PLS, anticorps MGC69126, anticorps MGC107782, anticorps AI047818, anticorps CATC, anticorps cb912, anticorps ik:tdsubc_1h2, anticorps sb:cb146, anticorps wu:fb34g12, anticorps wu:fj58d01, anticorps cathepsin C, anticorps cathepsin C L homeolog, anticorps cathepsin CPC1, anticorps CTSC, anticorps ctsc.L, anticorps ctsc, anticorps TP03_0357, anticorps CMU_003360, anticorps CPC1, anticorps NAEGRDRAFT_80477, anticorps NAEGRDRAFT_37577, anticorps Ctsc, anticorps Smp_183330
- Sujet
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CTSC is a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in CTSC have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.
Alias Symbols: CPPI, DPP1, DPPI, HMS, JP, JPD, PALS, PLS, DPP-I
Protein Interaction Partner: SUMO1, UBC, NEDD8, ARMC9, ANKMY2, ARIH1, UBA2, ADSL, FBXO6, XRN2, CAPN1, CD81, CTSC, CTSL,
Protein Size: 463 - Poids moléculaire
- 8 kDa
- ID gène
- 1075
- NCBI Accession
- NM_001814, NP_001805
- UniProt
- P53634
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