ST5 anticorps (Middle Region)
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- Antigène Voir toutes ST5 Anticorps
- ST5 (Suppression of Tumorigenicity 5 (ST5))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ST5 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- VPKPKRTFEY EADKNPKSKP SNGLPPSPTP AAPPPLPSTP APPVTRRPKK
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against ST5. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human ST5
- Top Product
- Discover our top product ST5 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 1137 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- ST5 (Suppression of Tumorigenicity 5 (ST5))
- Autre désignation
- ST5 (ST5 Produits)
- Synonymes
- anticorps zgc:91902, anticorps wu:fc11b09, anticorps si:ch211-208c6.1, anticorps ST5, anticorps DKFZp459D1230, anticorps hts1, anticorps p126, anticorps dennd2b, anticorps DENND2B, anticorps HTS1, anticorps 2010004M01Rik, anticorps 2610305K15Rik, anticorps suppression of tumorigenicity 5, anticorps st5, anticorps ST5, anticorps St5
- Sujet
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This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.
Alias Symbols: DENND2B, HTS1, MGC33090, p126
Protein Interaction Partner: SMAD2, UBC, ABL1, SFN,
Protein Size: 1137 - Poids moléculaire
- 126 kDa
- ID gène
- 6764
- NCBI Accession
- NM_005418, NP_005409
- UniProt
- P78524
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