TCHP anticorps (C-Term)
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- Antigène Voir toutes TCHP Anticorps
- TCHP (Trichoplein, Keratin Filament Binding (TCHP))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval, Saccharomyces cerevisiae
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TCHP est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- IQEKIEQNRR AQEESLKHRE QLIRNLEEVR ELARREKEES EKLKSARKQE
- Homologie
- Cow: 100%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Yeast: 91%
- Attributs du produit
- This is a rabbit polyclonal antibody against TCHP. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human TCHP
- Top Product
- Discover our top product TCHP Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 498 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Embryonic Stem Cells Exhibit mRNA Isoform Specific Translational Regulation." dans: PLoS ONE, Vol. 11, Issue 1, pp. e0143235, (2016) (PubMed).
: "
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Embryonic Stem Cells Exhibit mRNA Isoform Specific Translational Regulation." dans: PLoS ONE, Vol. 11, Issue 1, pp. e0143235, (2016) (PubMed).
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- Antigène
- TCHP (Trichoplein, Keratin Filament Binding (TCHP))
- Autre désignation
- TCHP (TCHP Produits)
- Synonymes
- anticorps TpMs, anticorps A930031F18Rik, anticorps AV279199, anticorps RGD1310813, anticorps zgc:136634, anticorps trichoplein keratin filament binding, anticorps trichoplein, keratin filament binding, anticorps trichoplein, keratin filament binding L homeolog, anticorps TCHP, anticorps tchp, anticorps Tchp, anticorps tchp.L
- Sujet
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TCHP is a tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. It inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. It may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. And it also may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.
Alias Symbols: MGC10854, TpMs
Protein Interaction Partner: CCDC172, MIPOL1, DYDC1, KRT40, LZTS2, NME7, NDOR1, MKRN3, TRIM27, NAB2, KRT15, CDR2, UBC, LATS2, CUL4A, CCDC85B, TEX11, VIM, KRT18, KRT16, KRT14, KRT8, KRT6A, KRT5,
Protein Size: 498 - Poids moléculaire
- 61 kDa
- ID gène
- 84260
- NCBI Accession
- NM_032300, NP_115676
- UniProt
- Q9BT92
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