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PYM anticorps (C-Term)

WIBG Reactivité: Humain, Souris, Boeuf (Vache), Chien, Cheval, Cobaye, Lapin, Rat, Saccharomyces cerevisiae, Porc WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2788485
  • Antigène Voir toutes PYM (WIBG) Anticorps
    PYM (WIBG) (Partner of Y14 and mago (WIBG))
    Épitope
    • 8
    • 8
    • 7
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 29
    • 18
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Boeuf (Vache), Chien, Cheval, Cobaye, Lapin, Rat, Saccharomyces cerevisiae, Porc
    Hôte
    • 27
    • 2
    Lapin
    Clonalité
    • 27
    • 2
    Polyclonal
    Conjugué
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PYM est non-conjugé
    Application
    • 21
    • 15
    • 13
    • 5
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    KKIKNLKKKL RQVEELQQRI QAGEVSQPSK EQLEKLARRR ALEEELEDLE
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%, Yeast: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against WIBG. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C terminal region of human WIBG
    Top Product
    Discover our top product WIBG Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 204 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    PYM (WIBG) (Partner of Y14 and mago (WIBG))
    Autre désignation
    WIBG (WIBG Produits)
    Synonymes
    anticorps BEST:HL05757, anticorps CG10330, anticorps CG30176, anticorps Dmel\\CG30176, anticorps PYM, anticorps Pym, anticorps UD3, anticorps A030010B05Rik, anticorps zgc:65891, anticorps zgc:77281, anticorps Partner of Y14 and Mago, anticorps Wibg protein, anticorps PYM homolog 1, exon junction complex associated factor L homeolog, anticorps PYM homolog 1, exon junction complex associated factor, anticorps Pym, anticorps wibg, anticorps pym1.L, anticorps PYM1, anticorps Pym1, anticorps pym1
    Sujet
    WIBG is a key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. It acts as a EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. It interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions.
    Alias Symbols: MGC13064, PYM
    Protein Interaction Partner: RTN4IP1, UBC, RPS19, RPS14, RPS13, RPS12, RPS10, RPS9, RPS8, RPS7, RPS6, RPS5, RPS4X, RPS3A, RPS3, RPS2, FAU, BYSL, ZNF503, PNO1, KCMF1, TSR1, RPS27L, UBQLN1, RPS29, RPS28, RPS27, RPS26, RPS25, RPS24, RPS23, RPS20, RPS18, RPS16, RPS15A, TARDBP, MAGOH, TOE
    Protein Size: 204
    Poids moléculaire
    23 kDa
    ID gène
    84305
    NCBI Accession
    NM_032345, NP_115721
    UniProt
    Q9BRP8
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