IL-18 anticorps (C-Term)
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- Antigène Voir toutes IL-18 (IL18) Anticorps
- IL-18 (IL18) (Interleukin 18 (IL18))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IL-18 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- IIFFQRSVPG HDNKMQFESS SYEGYFLACE KERDLFKLIL KKEDELGDRS
- Homologie
- Human: 100%, Mouse: 79%, Rat: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against IL18. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human IL18
- Top Product
- Discover our top product IL18 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 193 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- IL-18 (IL18) (Interleukin 18 (IL18))
- Autre désignation
- IL18 (IL18 Produits)
- Synonymes
- anticorps Igif, anticorps Il-18, anticorps IL-18, anticorps IGIF, anticorps ChIL-18, anticorps IL-1g, anticorps IL1F4, anticorps IL18, anticorps interleukin 18, anticorps Il18, anticorps IL18
- Sujet
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The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.
Alias Symbols: IGIF, IL-18, IL-1g, IL1F4, MGC12320
Protein Interaction Partner: CASK, UBC, IL1RL2, IL18RAP, IL18R1, IL18BP, CASP4, CASP3, CASP1,
Protein Size: 193 - Poids moléculaire
- 18 kDa
- ID gène
- 3606
- NCBI Accession
- NM_001562, NP_001553
- UniProt
- Q14116
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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