ACER1 anticorps (C-Term)

N° du produit ABIN2788591

Détail du produit anti-ACER1 anticorps

Antigène: ACER1 (Alkaline Ceramidase 1 (ACER1))

Épitope: C-Term

Reactivité: Humain, Rat, Boeuf (Vache), Cobaye, Lapin, Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACER1 est non-conjugé

Application: Western Blotting (WB)

Séquence: VNAYALNSIA LHILYIVCQE YRKTSNKELR HLIEVSVVLW AVALTSWISD

Homologie: Cow: 79%, Dog: 92%, Guinea Pig: 75%, Human: 100%, Pig: 85%, Rabbit: 86%, Rat: 77%

Attributs du produit: This is a rabbit polyclonal antibody against ACER1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ACER1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 264 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ACER1

Antigène: ACER1 (Alkaline Ceramidase 1 (ACER1))

Autre désignation: ACER1 (ACER1 Produits)

Synonymes: anticorps ASAH3, anticorps asah3, anticorps zgc:110285, anticorps ALKCDase1, anticorps 2310024P18Rik, anticorps AI662009, anticorps Alkcdase1, anticorps Asah3, anticorps Cer1, anticorps alkaline ceramidase 1, anticorps ACER1, anticorps acer1, anticorps Acer1

Sujet: ACER1 hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. It has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo-phytosphingosine or D-erythro-dihydrosphingosine as a backbone. It may have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids.
Alias Symbols: ASAH3, MGC138327, MGC138329, ALKCDase1
Protein Size: 264

Poids moléculaire: 31 kDa

ID gène: 125981

NCBI Accession: NM_133492, NP_597999

UniProt: Q8TDN7