Hexosaminidase A anticorps (C-Term)
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- Antigène Voir toutes Hexosaminidase A (HEXA) Anticorps
- Hexosaminidase A (HEXA)
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Épitope
- C-Term
- Reactivité
- Humain, Souris, Rat, Porc, Chien, Cobaye, Cheval, Lapin, Mouton, Boeuf (Vache)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Hexosaminidase A est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- WKDFYIVEPL AFEGTPEQKA LVIGGEACMW GEYVDNTNLV PRLWPRAGAV
- Homologie
- Cow: 93%, Dog: 85%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%, Sheep: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against HEXA. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human HEXA
- Top Product
- Discover our top product HEXA Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 529 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- Hexosaminidase A (HEXA)
- Autre désignation
- HEXA (HEXA Produits)
- Synonymes
- anticorps TSD, anticorps fc04h11, anticorps wu:fc04h11, anticorps wu:fv09f06, anticorps si:dkey-35i22.2, anticorps HEXA, anticorps Hex-1, anticorps zgc:112084, anticorps hexosaminidase subunit alpha, anticorps hexosaminidase B (beta polypeptide), anticorps CUGBP Elav-like family member 6, anticorps hexosaminidase A, anticorps hexosaminidase A (alpha polypeptide), anticorps beta-hexosaminidase subunit alpha-like, anticorps HEXA, anticorps hexb, anticorps CELF6, anticorps Hexa, anticorps hexa, anticorps LOC100228061
- Sujet
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This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).
Alias Symbols: MGC99608, TSD
Protein Interaction Partner: H2AFV, WDR61, UBA6, UBR7, C9orf78, HERC4, FKBP9, PDCD10, NUBP2, GTF3C4, HIST1H2BO, XPNPEP1, EZR, RAD23A, PCNA, KTN1, HK1, GDI1, CAPZB, AHCY, ACAT2, FBXO6, H2AFX, GM2A, USP22,
Protein Size: 529 - Poids moléculaire
- 48 kDa
- ID gène
- 3073
- NCBI Accession
- NM_000520, NP_000511
- UniProt
- P06865
- Pathways
- Sensory Perception of Sound, Glycosaminoglycan Metabolic Process
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