SORD anticorps (N-Term)

N° du produit ABIN2788686

Détail du produit anti-SORD anticorps

Antigène: SORD (Sorbitol Dehydrogenase (SORD))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Mouton, Chien, Lapin, Porc, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SORD est non-conjugé

Application: Western Blotting (WB)

Séquence: ASGTVEKVGS SVKHLKPGDR VAIEPGAPRE NDEFCKMGRY NLSPSIFFCA

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 83%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 86%, Rat: 93%, Sheep: 79%

Attributs du produit: This is a rabbit polyclonal antibody against SORD. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SORD

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 357 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SORD

Antigène: SORD (Sorbitol Dehydrogenase (SORD))

Autre désignation: SORD (SORD Produits)

Sujet: Sorbitol dehydrogenase (SORD, EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1, MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
Alias Symbols: SORD1
Protein Interaction Partner: SORD, SUMO2, UBC, C12orf10, BCCIP, NAGK, CHORDC1, ACOT7, DDX39A, GDA, THOP1, TCEA1, TALDO1, SMS, PLS3, PGD, NME1, LDHA, FDPS, RELA, C16orf13, FLAD1, PIEZO1, TPM1, RANGAP1, RAD23A, PFDN4, GCLM, ETFA, AKR1B1, NUDCD2, LOC440434, TIPRL, SHBG,
Protein Size: 357

Poids moléculaire: 38 kDa

ID gène: 6652

NCBI Accession: NM_003104, NP_003095

UniProt: Q00796