Endothelin 3 anticorps (C-Term)
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- Antigène Voir toutes Endothelin 3 (EDN3) Anticorps
- Endothelin 3 (EDN3)
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Épitope
- C-Term
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Reactivité
- Humain, Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Endothelin 3 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LHFCTQTLDV SSNSRTAEKT DKEEEGKVRG ANRGLCQRRL KSRTNKASRL
- Homologie
- Human: 100%, Pig: 85%
- Attributs du produit
- This is a rabbit polyclonal antibody against EDN3. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human EDN3
- Top Product
- Discover our top product EDN3 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 219 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- Endothelin 3 (EDN3)
- Autre désignation
- EDN3 (EDN3 Produits)
- Synonymes
- anticorps et-3, anticorps EDN3, anticorps ET-3, anticorps ET3, anticorps HSCR4, anticorps PPET3, anticorps WS4B, anticorps 114CH19, anticorps ls, anticorps tmgc48, anticorps Et3, anticorps RGD1564825, anticorps preproET-3, anticorps endothelin-3 L homeolog, anticorps endothelin 3, anticorps edn3.L, anticorps EDN3, anticorps Edn3
- Sujet
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The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.
Alias Symbols: ET3, MGC15067, MGC61498, ET-3, WS4B, HSCR4, PPET3
Protein Interaction Partner: EDNRB, EDNRA, CMA1, CTSE, KEL,
Protein Size: 219 - Poids moléculaire
- 24 kDa
- ID gène
- 1908
- NCBI Accession
- NM_207032, NP_996915
- UniProt
- P14138
- Pathways
- Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
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