KPNB1 anticorps (N-Term)

N° du produit ABIN2788708

Détail du produit anti-KPNB1 anticorps

Antigène: KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KPNB1 est non-conjugé

Application: Western Blotting (WB)

Séquence: EHMKESTLEA IGYICQDIDP EQLQDKSNEI LTAIIQGMRK EEPSNNVKLA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against KPNB1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 876 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KPNB1

Antigène: KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

Autre désignation: KPNB1 (KPNB1 Produits)

Synonymes: anticorps Afu1g15720, anticorps AO090005001133, anticorps imb1, anticorps impnb, anticorps ipo1, anticorps ipob, anticorps ntf97, anticorps IMB1, anticorps IPO1, anticorps IPOB, anticorps Impnb, anticorps NTF97, anticorps AA409963, anticorps importin beta-1 subunit, anticorps Importin beta-1 subunit, anticorps karyopherin (importin) beta 1 L homeolog, anticorps importin beta 1, anticorps karyopherin subunit beta 1, anticorps karyopherin (importin) beta 1, anticorps AFUA_1G15720, anticorps AOR_1_1974174, anticorps Bm1_57540, anticorps PMAA_065830, anticorps AFLA_083750, anticorps TSTA_085870, anticorps BDBG_07509, anticorps MCYG_00039, anticorps kpnb1.L, anticorps LOC100533387, anticorps KPNB1, anticorps Kpnb1

Sujet: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
Alias Symbols: IMB1, IPO1, IPOB, Impnb, MGC2155, MGC2156, MGC2157, NTF97
Protein Interaction Partner: HUWE1, UBC, FUS, SUMO2, SUMO3, STAU1, MDM2, EED, rev, CUL2, NLK, FBXO6, DYRK1B, CLK3, CDK11A, EGFR, SAMHD1, UBD, PTMA, ADRB2, RASSF5, AICDA, UBL4A, VCAM1, TAF10, NOS2, SMAD2, TAF8, TAF3, ITGA4, FN1, ERBB2, CFTR, YWHAE, SMURF1, ECT2, BARD1, MDC1, TP53BP1,
Protein Size: 876

Poids moléculaire: 96 kDa

ID gène: 3837

NCBI Accession: NM_002265, NP_002256

UniProt: Q14974

Pathways: Protein targeting to Nucleus