PVRL1 anticorps (N-Term)
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- Antigène Voir toutes PVRL1 Anticorps
- PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PVRL1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- QLNLTVMAKP TNWIEGTQAV LRAKKGQDDK VLVATCTSAN GKPPSVVSWE
- Homologie
- Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against PVRL1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product PVRL1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 517 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))
- Autre désignation
- PVRL1 (PVRL1 Produits)
- Synonymes
- anticorps CD111, anticorps CLPED1, anticorps ED4, anticorps HIgR, anticorps HVEC, anticorps OFC7, anticorps PRR, anticorps PRR1, anticorps PVRR, anticorps PVRR1, anticorps SK-12, anticorps nectin-1, anticorps prr1, anticorps PVRL1, anticorps pvrl1, anticorps AI835281, anticorps AW549174, anticorps Cd111, anticorps HveC, anticorps cd111, anticorps cd112, anticorps clped1, anticorps ed4, anticorps higr, anticorps hveb, anticorps hvec, anticorps nectin-2, anticorps ofc7, anticorps prr, anticorps prr2, anticorps pvrl2, anticorps pvrl2.L, anticorps pvrr, anticorps pvrr1, anticorps pvrr2, anticorps sk-12, anticorps nectin cell adhesion molecule 1, anticorps nectin-1, anticorps Poliovirus receptor-related protein 1, anticorps poliovirus receptor-related 1 (herpesvirus entry mediator C), anticorps nectin cell adhesion molecule 2 L homeolog, anticorps NECTIN1, anticorps LOC100145553, anticorps pvrl1, anticorps nectin1, anticorps Nectin1, anticorps PVRL1, anticorps nectin2.L
- Sujet
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This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
Alias Symbols: CD111, CLPED1, ED4, HIgR, HVEC, MGC142031, MGC16207, OFC7, PRR, PRR1, PVRR, PVRR1, SK-12, nectin-1
Protein Interaction Partner: UBC, PVRL4, PVRL3, PVRL1, PARD3, PRNP, PVR, MLLT4,
Protein Size: 517 - Poids moléculaire
- 57 kDa
- ID gène
- 5818
- NCBI Accession
- NM_002855, NP_002846
- UniProt
- Q15223
- Pathways
- Cell-Cell Junction Organization
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