GBA anticorps (C-Term)

N° du produit ABIN2788767

Détail du produit anti-GBA anticorps

Antigène: GBA (Glucosidase, Beta, Acid (GBA))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Porc, Chien, Cheval, Lapin, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GBA est non-conjugé

Application: Western Blotting (WB)

Séquence: EGSQRVGLVA SQKNDLDAVA LMHPDGSAVV VVLNRSSKDV PLTIKDPAVG

Homologie: Cow: 92%, Dog: 86%, Guinea Pig: 86%, Horse: 85%, Human: 100%, Mouse: 83%, Pig: 100%, Rabbit: 86%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against GBA. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 536 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GBA

Antigène: GBA (Glucosidase, Beta, Acid (GBA))

Autre désignation: GBA (GBA Produits)

Synonymes: anticorps GBA1, anticorps GCB, anticorps GLUC, anticorps BETA-GLUCOSIDASE, anticorps T12J13.8, anticorps T12J13_8, anticorps beta glucosidase 25, anticorps PSPTO3318, anticorps PSPTO4290, anticorps GC, anticorps GCase, anticorps betaGC, anticorps glucosylceramidase beta, anticorps beta glucosidase 25, anticorps beta-glucosidase, anticorps Beta-glucosidase, anticorps glucosidase, beta, acid, anticorps glucosylceramidase, anticorps bglX-2, anticorps GBA, anticorps BGLU25, anticorps PSPTO_3318, anticorps bglX, anticorps bglA4, anticorps Gba, anticorps LOC100399524, anticorps bglA.2, anticorps bglX-2

Sujet: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Alias Symbols: GBA1, GCB, GLUC
Protein Interaction Partner: NUDCD1, UBC, ITCH, ATP6V1B1, SNCA, FBXO6, TCP1, CBL, NEDD4, PARK2, HSP90AA1, HSPA4, PSAP,
Protein Size: 536

Poids moléculaire: 59 kDa

ID gène: 2629

NCBI Accession: NM_000157, NP_000148

UniProt: P04062

Pathways: Cellular Glucan Metabolic Process