HARS1/Jo-1 anticorps (N-Term)
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- Antigène Voir toutes HARS1/Jo-1 (HARS1) Anticorps
- HARS1/Jo-1 (HARS1) (Histidyl-tRNA Synthetase (HARS1))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Cobaye, Cheval, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HARS1/Jo-1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- FVLKTPKGTR DYSPRQMAVR EKVFDVIIRC FKRHGAEVID TPVFELKETL
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against HARS. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human HARS
- Top Product
- Discover our top product HARS1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 509 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- HARS1/Jo-1 (HARS1) (Histidyl-tRNA Synthetase (HARS1))
- Autre désignation
- HARS (HARS1 Produits)
- Synonymes
- anticorps HRS, anticorps USH3B, anticorps MMHRS, anticorps Dnd1, anticorps HARSL, anticorps histidyl-tRNA synthetase, anticorps HARS, anticorps Hars
- Sujet
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Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.
Alias Symbols: FLJ20491, HRS, USH3B
Protein Interaction Partner: UBC, AARSD1, ACBD3, ELAC2, XPO5, THG1L, NSUN2, RPUSD2, SNF8, IPO7, EFTUD2, TTC1, SHMT1, PFDN1, GTF2E1, FEN1, CALU, PI4KA, G6PD, EIF2D, ANXA5, UBD, SUMO1, TNIK, STAM, EIF3I, EEF1G, RPL5, EEF1B2, TARS,
Protein Size: 509 - Poids moléculaire
- 56 kDa
- ID gène
- 3035
- NCBI Accession
- NM_002109, NP_002100
- UniProt
- P12081
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