WWOX anticorps (C-Term)
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- Antigène Voir toutes WWOX Anticorps
- WWOX (WW Domain Containing Oxidoreductase (WWOX))
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Épitope
- C-Term
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Chien, Porc, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp WWOX est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- DDNPTKPTTR QRYDGSTTAM EILQGRDFTG KVVVVTGANS GIGFETAKSF
- Homologie
- Cow: 100%, Dog: 92%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against WWOX. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product WWOX Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 189 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- WWOX (WW Domain Containing Oxidoreductase (WWOX))
- Autre désignation
- WWOX (WWOX Produits)
- Synonymes
- anticorps CG7221, anticorps DmWWOX, anticorps Dmel\\CG7221, anticorps anon-EST:Posey177, anticorps GB11795, anticorps WWOX, anticorps D16S432E, anticorps FOR, anticorps FRA16D, anticorps HHCMA56, anticorps PRO0128, anticorps SDR41C1, anticorps WOX1, anticorps zgc:55975, anticorps 5330426P09Rik, anticorps 9030416C10Rik, anticorps WW domain containing oxidoreductase, anticorps WW domain-containing oxidoreductase, anticorps Wwox, anticorps LOC411815, anticorps WWOX, anticorps CpipJ_CPIJ004939, anticorps MCYG_01584, anticorps VDBG_05631, anticorps VDBG_01326, anticorps VDBG_06753, anticorps Tsp_03967, anticorps LOC100284583, anticorps wwox
- Sujet
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WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90 % identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms.
Alias Symbols: D16S432E, FOR, FRA16D, HHCMA56, PRO0128, SDR41C1, WOX1
Protein Interaction Partner: ITCH, TRIM28, HUWE1, UBC, ATM, RPRD2, CYFIP1, SPG20, SNRNP200, ACIN1, SLC4A1AP, DHX30, SCAF8, XRN2, GABARAPL2, SEC23IP, HNRNPUL1, DIDO1, CPSF6, SF3B2, SF3A3, SRSF10, USP39, IGF2BP2, IGF2BP3, IGF2BP1, PAICS, PRPF8, CCT2, CCT7, NOP56, DDX17, SEC23A, BAIAP2,
Protein Size: 189 - Poids moléculaire
- 21 kDa
- ID gène
- 51741
- NCBI Accession
- NM_130791, NP_570607
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