SCARB2 anticorps (N-Term)
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- Antigène Voir toutes SCARB2 Anticorps
- SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SCARB2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- VARVFQKAVD QSIEKKIVLR NGTEAFDSWE KPPLPVYTQF YFFNVTNPEE
- Homologie
- Cow: 86%, Dog: 86%, Horse: 79%, Human: 100%, Mouse: 79%, Pig: 86%, Rat: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against SCARB2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product SCARB2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 478 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))
- Autre désignation
- SCARB2 (SCARB2 Produits)
- Synonymes
- anticorps cd36l2, anticorps fi13c07, anticorps chunp6914, anticorps wu:fi13c07, anticorps SCARB2, anticorps scarb2, anticorps AMRF, anticorps CD36L2, anticorps EPM4, anticorps HLGP85, anticorps LGP85, anticorps LIMP-2, anticorps LIMPII, anticorps SR-BII, anticorps 9330185J12Rik, anticorps Cd36l2, anticorps MLGP85, anticorps LimpII, anticorps scavenger receptor class B, member 2a, anticorps scavenger receptor class B member 2, anticorps scavenger receptor class B, member 2, anticorps scarb2a, anticorps SCARB2, anticorps scarb2, anticorps Scarb2
- Sujet
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The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF).
Alias Symbols: AMRF, CD36L2, HLGP85, LIMPII, SR-BII, EPM4, LGP85, LIMP-2
Protein Interaction Partner: UBC, ATP4A, TAF15, NONO, HSPD1, DDX1, ATP6V1B1, Ap1g1, AP3S2, AP3S1, THBS1,
Protein Size: 478 - Poids moléculaire
- 53 kDa
- ID gène
- 950
- NCBI Accession
- NM_005506, NP_005497
- UniProt
- Q14108
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