RPL7A anticorps (C-Term)

N° du produit ABIN2788883

Détail du produit anti-RPL7A anticorps

Antigène: RPL7A (Ribosomal Protein L7a (RPL7A))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPL7A est non-conjugé

Application: Western Blotting (WB)

Séquence: KLVEAIRTNY NDRYDEIRRH WGGNVLGPKS VARIAKLEKA KAKELATKLG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RPL7A. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 266 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RPL7A

Antigène: RPL7A (Ribosomal Protein L7a (RPL7A))

Autre désignation: RPL7A (RPL7A Produits)

Synonymes: anticorps CG3314, anticorps Dmel\\CG3314, anticorps L7A, anticorps L7a, anticorps Rp L7A, anticorps Surf-3/rpL7a, anticorps Surf3/rpL7a, anticorps rpl7a, anticorps surf3, anticorps SURF3, anticorps TRUP, anticorps Surf3, anticorps wu:fa95b03, anticorps zgc:73183, anticorps zgc:86667, anticorps Ribosomal protein L7A, anticorps 60S ribosomal protein L7a, anticorps ribosomal protein L7a, anticorps ribosomal protein L7A, anticorps RpL7A, anticorps LOC100525692, anticorps rpl7a, anticorps RPL7A, anticorps Rpl7a

Sujet: Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with the trk proto-oncogene to form the chimeric oncogene trk-2h, which encodes an oncoprotein consisting of the N terminus of ribosomal protein L7a fused to the receptor tyrosine kinase domain of trk. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Alias Symbols: SURF3, TRUP, L7A
Protein Interaction Partner: HUWE1, UBC, TP53, SUMO2, CEP250, STAU1, MDM2, EED, RNF2, EEF1E1, AIMP1, DARS, RPL36, RPLP0, RPL26, RPL23A, RPL21, RPL15, RPL13, QARS, EIF2S1, TRAP1, PARK2, FBXO6, TARDBP, IGSF8, ICAM1, PAN2, SOCS3, UBL4A, VCAM1, ITGA4, FN1, CTBP2, MAGOH, EIF4A3, UPF1, ESR
Protein Size: 266

Poids moléculaire: 29 kDa

ID gène: 6130

NCBI Accession: NM_000972, NP_000963

UniProt: P62424