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RASGRP4 anticorps (N-Term)

RASGRP4 Reactivité: Humain, Porc WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2789029
  • Antigène Voir toutes RASGRP4 Anticorps
    RASGRP4 (RAS Guanyl Releasing Protein 4 (RASGRP4))
    Épitope
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 10
    • 2
    • 1
    Humain, Porc
    Hôte
    • 8
    • 3
    Lapin
    Clonalité
    • 9
    • 2
    Polyclonal
    Conjugué
    • 11
    Cet anticorp RASGRP4 est non-conjugé
    Application
    • 10
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    FWATVAREGN SAQRRLGDSS DLLSPGGPGP PLPMSSPGLG KKRKVSLLFD
    Homologie
    Human: 100%, Pig: 92%
    Attributs du produit
    This is a rabbit polyclonal antibody against RASGRP4. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product RASGRP4 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 576 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    RASGRP4 (RAS Guanyl Releasing Protein 4 (RASGRP4))
    Autre désignation
    RASGRP4 (RASGRP4 Produits)
    Synonymes
    anticorps RASGRP4, anticorps RAS guanyl releasing protein 4, anticorps RASGRP4, anticorps rasgrp4, anticorps Rasgrp4
    Sujet
    The protein encoded by this gene is a member of the Ras guanyl nucleotide-releasing protein (RasGRP) family of Ras guanine nucleotide exchange factors. It contains a Ras exchange motif, a diacylglycerol-binding domain, and two calcium-binding EF hands. This protein was shown to activate H-Ras in a cation-dependent manner in vitro. Expression of this protein in myeloid cell lines was found to be correlated with elevated level of activated RAS protein, and the RAS activation can be greatly enhanced by phorbol ester treatment, which suggested a role of this protein in diacylglycerol regulated cell signaling pathways. Studies of a mast cell leukemia cell line expressing substantial amounts of abnormal transcripts of this gene indicated that this gene may play an important role in the final stages of mast cell development. Multiple transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: -
    Protein Interaction Partner: HRAS, RAP1A,
    Protein Size: 576
    Poids moléculaire
    63 kDa
    ID gène
    115727
    NCBI Accession
    NM_001146207, NP_001139679
    UniProt
    C0LTP7
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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