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EXOSC9 anticorps (N-Term)

EXOSC9 Reactivité: Humain, Souris, Rat, Porc, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien, Cheval WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2789034
  • Antigène Voir toutes EXOSC9 Anticorps
    EXOSC9 (Exosome Component 9 (EXOSC9))
    Épitope
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Porc, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien, Cheval
    Hôte
    • 12
    • 2
    • 1
    Lapin
    Clonalité
    • 13
    • 2
    Polyclonal
    Conjugué
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EXOSC9 est non-conjugé
    Application
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    ERRFLLRAIE EKKRLDGRQT YDYRNIRISF GTDYGCCIVE LGKTRVLGQV
    Homologie
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against EXOSC9. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product EXOSC9 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 355 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    EXOSC9 (Exosome Component 9 (EXOSC9))
    Autre désignation
    EXOSC9 (EXOSC9 Produits)
    Synonymes
    anticorps scl75, anticorps im:6909054, anticorps zgc:101680, anticorps PM/Scl-75, anticorps PMSCL1, anticorps RRP45, anticorps Rrp45p, anticorps p5, anticorps p6, anticorps Pmscl1, anticorps exosome component 9 L homeolog, anticorps exosome component 9, anticorps exosc9.L, anticorps exosc9, anticorps EXOSC9, anticorps Exosc9
    Sujet
    EXOSC9 is a non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC9 binds to ARE-containing RNAs.
    Alias Symbols: PM/Scl-75, PMSCL1, RRP45, Rrp45p, p5, p6
    Protein Interaction Partner: UBC, EXOSC4, MPG, AICDA, CSNK2A1, EXOSC5, EXOSC10, EXOSC3, EXOSC2, DIS3, DIS3L, CHMP4B, CAND1, COPS5, CUL3, SUMO2, UBE2I, EXOSC1, SKIV2L2, EXOSC6, DDX39A, MPP6, EXOSC7, EXOSC8, EXOSC9, DDX39B,
    Protein Size: 355
    Poids moléculaire
    39 kDa
    ID gène
    5393
    NCBI Accession
    NM_005033, NP_005024
    UniProt
    Q06265
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