FPGT anticorps (C-Term)
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- Antigène Voir toutes FPGT Anticorps
- FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Cobaye, Boeuf (Vache), Chien, Porc, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FPGT est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- TSLNVVVLNN SKFYHIGTTE EYLFYFTSDN SLKSELGLQS ITFSIFPDIP
- Homologie
- Cow: 86%, Dog: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 79%, Pig: 100%, Rat: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against FPGT. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human FPGT
- Top Product
- Discover our top product FPGT Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 594 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))
- Autre désignation
- FPGT (FPGT Produits)
- Synonymes
- anticorps DDBDRAFT_0186414, anticorps DDBDRAFT_0233144, anticorps DDB_0186414, anticorps DDB_0233144, anticorps FPGT, anticorps DKFZp459M111, anticorps fpgt, anticorps zgc:110694, anticorps GFPP, anticorps 1700016E03Rik, anticorps fucose-1-phosphate guanylyltransferase, anticorps fucose-1-phosphate guanylyltransferase L homeolog, anticorps fpgt, anticorps FPGT, anticorps fpgt.L, anticorps Fpgt
- Sujet
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L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose, the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream TNNI3 interacting kinase (TNNI3K) gene.
Alias Symbols: GFPP
Protein Interaction Partner: NLN,
Protein Size: 594 - Poids moléculaire
- 66 kDa
- ID gène
- 8790
- NCBI Accession
- NM_003838, NP_003829
- UniProt
- O14772
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