HLA-E anticorps (C-Term)
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- Antigène Voir toutes HLA-E Anticorps
- HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HLA-E est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- IPIVGIIAGL VLLGSVVSGA VVAAVIWRKK SSGGKGGSYS KAEWSDSAQG
- Homologie
- Human: 100%, Mouse: 100%, Pig: 92%
- Attributs du produit
- This is a rabbit polyclonal antibody against HLA-E. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product HLA-E Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 358 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
- Autre désignation
- HLA-E (HLA-E Produits)
- Synonymes
- anticorps EA1.2, anticorps EA2.1, anticorps HLA-6.2, anticorps MHC, anticorps QA1, anticorps major histocompatibility complex, class I, E, anticorps HLA-E, anticorps PATR-E
- Sujet
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HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.
Alias Symbols: DKFZp686P19218, EA1.2, EA2.1, HLA-6.2, MHC, QA1
Protein Interaction Partner: UBC, CALR, TAP2, UBD, PPP1R16A, KLRD1, KLRC2, CD8A, KLRC1, HLA-E, B2M,
Protein Size: 358 - Poids moléculaire
- 38 kDa
- ID gène
- 3133
- NCBI Accession
- NM_005516, NP_005507
- UniProt
- P13747
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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