PD-L1 anticorps (C-Term)
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- Antigène Voir toutes PD-L1 Anticorps
- PD-L1 (CD274 (PD-L1))
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Épitope
- C-Term
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Reactivité
- Humain, Porc, Boeuf (Vache)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PD-L1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- NVTSTLRINT TTNEIFYCTF RRLDPEENHT AELVIPELPL AHPPNERTHL
- Homologie
- Cow: 79%, Human: 100%, Pig: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against CD274. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product PD-L1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 290 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PD-L1 (CD274 (PD-L1))
- Autre désignation
- CD274 (PD-L1 Produits)
- Synonymes
- anticorps B7-H, anticorps B7H1, anticorps PD-L1, anticorps PDCD1L1, anticorps PDCD1LG1, anticorps PDL1, anticorps A530045L16Rik, anticorps B7h1, anticorps Pdcd1l1, anticorps Pdcd1lg1, anticorps Pdl1, anticorps RGD1566211, anticorps CD274 molecule, anticorps CD274 antigen, anticorps programmed cell death 1 ligand 2, anticorps CD274, anticorps Cd274, anticorps PDCD1LG2
- Sujet
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CD274 is involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
Alias Symbols: B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1, PDCD1LG1, PDL1
Protein Interaction Partner: PDCD1, CD80, PTPN11,
Protein Size: 290 - Poids moléculaire
- 32 kDa
- ID gène
- 29126
- NCBI Accession
- NM_014143, NP_054862
- UniProt
- Q9NZQ7
- Pathways
- Cancer Immune Checkpoints
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