SOCS2 anticorps (C-Term)

N° du produit ABIN2789498

Détail du produit anti-SOCS2 anticorps

Antigène: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Porc, Boeuf (Vache), Chien, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS2 est non-conjugé

Application: Western Blotting (WB)

Séquence: KQFDSVVHLI DYYVQMCKDK RTGPEAPRNG TVHLYLTKPL YTSAPSLQHL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SOCS2. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 198 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SOCS2

Antigène: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Autre désignation: SOCS2 (SOCS2 Produits)

Synonymes: anticorps CIS2, anticorps Cish2, anticorps SOCS-2, anticorps SSI-2, anticorps SSI2, anticorps STATI2, anticorps Cish1, anticorps Socs-1, anticorps Socs-2, anticorps si:dkey-202b22.1, anticorps socs2, anticorps cis2, anticorps ssi2, anticorps cish2, anticorps ssi-2, anticorps socs-2, anticorps stati2, anticorps 8030460M17, anticorps AI527257, anticorps AW108012, anticorps D130043N08Rik, anticorps JAB, anticorps hg, anticorps Cradd, anticorps Socs2, anticorps suppressor of cytokine signaling 2, anticorps suppressor of cytokine signaling 1, anticorps death domain-containing protein CRADD, anticorps suppressor of cytokine signaling 2 S homeolog, anticorps SOCS2, anticorps Socs1, anticorps Socs2, anticorps socs2, anticorps LOC100716104, anticorps socs2.S

Sujet: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon (IFN)-gamma. The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control.
Alias Symbols: CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2
Protein Interaction Partner: Tceb1, CUL5, UBC, FLT3, ARFIP2, TPD52, PLA2G1B, BMI1, SOCS3, LCK, GHR, CCNC, RYBP, PTK2B, RNF7, TCEB2, EPOR, PTK2, PRLR, INSR, IGF1R, SOCS1,
Protein Size: 198

Poids moléculaire: 22 kDa

ID gène: 8835

NCBI Accession: NM_003877, NP_003868

UniProt: O14508

Pathways: Signalistation JAK/STAT, Response to Growth Hormone Stimulus