PDE6B anticorps (N-Term)

N° du produit ABIN2789554

Détail du produit anti-PDE6B anticorps

Antigène: PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE6B est non-conjugé

Application: Western Blotting (WB)

Séquence: LSMPIVNKKE EIVGVATFYN RKDGKPFDEQ DEVLMESLTQ FLGWSVMNTD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against PDE6B. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 575 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PDE6B

Antigène: PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))

Autre désignation: PDE6B (PDE6B Produits)

Synonymes: anticorps CSNB3, anticorps CSNBAD2, anticorps PDEB, anticorps RP40, anticorps rd1, anticorps PDBS, anticorps RCD-1, anticorps Pdeb, anticorps r, anticorps rd, anticorps rd-1, anticorps rd10, anticorps phosphodiesterase 6B, anticorps phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide, anticorps PDE6B, anticorps Pde6b

Sujet: Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CSNB3, CSNBAD2, PDEB, RP40, rd1
Protein Interaction Partner: PPP1CC,
Protein Size: 575

Poids moléculaire: 63 kDa

ID gène: 5158

NCBI Accession: NM_001145292, NP_001138764

UniProt: E7ETT3

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction