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WISP1 anticorps (Middle Region)

WISP1 Reactivité: Humain, Porc, Boeuf (Vache) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2789653
  • Antigène Voir toutes WISP1 Anticorps
    WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))
    Épitope
    • 15
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 40
    • 26
    • 4
    • 1
    • 1
    • 1
    • 1
    Humain, Porc, Boeuf (Vache)
    Hôte
    • 54
    • 5
    • 1
    • 1
    Lapin
    Clonalité
    • 57
    • 4
    Polyclonal
    Conjugué
    • 26
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp WISP1 est non-conjugé
    Application
    • 35
    • 21
    • 20
    • 13
    • 13
    • 8
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    VRPPRLWCPH PRRVSIPGHC CEQWVCEDDA KRPRKTAPRD TGAFDAVGEV
    Homologie
    Cow: 92%, Human: 100%, Pig: 85%
    Attributs du produit
    This is a rabbit polyclonal antibody against WISP1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product WISP1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 367 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))
    Autre désignation
    WISP1 (WISP1 Produits)
    Synonymes
    anticorps CCN4, anticorps WISP1c, anticorps WISP1i, anticorps WISP1tc, anticorps WISP-1, anticorps WISP1, anticorps si:ch211-38f10.2, anticorps AW146261, anticorps Elm1, anticorps zgc:172276, anticorps WNT1 inducible signaling pathway protein 1, anticorps WNT1 inducible signaling pathway protein 1a, anticorps WNT1-inducible-signaling pathway protein 1-like, anticorps WNT1 inducible signaling pathway protein 1b, anticorps WISP1, anticorps wisp1a, anticorps Wisp1, anticorps LOC100627044, anticorps wisp1b
    Sujet
    This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation. It also attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase.
    Alias Symbols: CCN4, WISP1c, WISP1i, WISP1tc
    Protein Interaction Partner: BGN, DCN, UGGT1,
    Protein Size: 367
    Poids moléculaire
    38 kDa
    ID gène
    8840
    NCBI Accession
    NM_003882, NP_003873
    UniProt
    O95388
    Pathways
    Signalisation WNT, Growth Factor Binding
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