KIR2DS2 anticorps (N-Term)
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- Antigène Voir toutes KIR2DS2 Anticorps
- KIR2DS2 (Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2))
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Épitope
- N-Term
- Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KIR2DS2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- ETVILQCWSD VRFEHFLLHR EGKYKDTLHL IGEHHDGVSK ANFSIGPMMQ
- Homologie
- Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against KIR2DS2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product KIR2DS2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 304 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- KIR2DS2 (Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2))
- Autre désignation
- KIR2DS2 (KIR2DS2 Produits)
- Synonymes
- anticorps 183ActI, anticorps CD158J, anticorps CD158b, anticorps NKAT5, anticorps cl-49, anticorps killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2, anticorps KIR2DS2
- Sujet
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Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response.
Alias Symbols: CU464060.1, 183ActI, CD158J, CD158b, NKAT5, cl-49
Protein Interaction Partner: TYROBP, HLA-C, KIR2DS2,
Protein Size: 304 - Poids moléculaire
- 32 kDa
- ID gène
- 100132285
- NCBI Accession
- NM_012312, NP_036444
- UniProt
- D0UWM7
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