LIMS1 anticorps (C-Term)
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- Antigène Voir toutes LIMS1 Anticorps
- LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Chévre
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp LIMS1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- VNCFACSTCN TKLTLKNKFV EFDMKPVCKK CYEKFPLELK KRLKKLAETL
- Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against LIMS1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product LIMS1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 387 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
- Autre désignation
- LIMS1 (LIMS1 Produits)
- Synonymes
- anticorps PINCH, anticorps PINCH-1, anticorps PINCH1, anticorps Pinch1, anticorps RGD1560732, anticorps LIMS3, anticorps LIMS3L, anticorps 2310016J22Rik, anticorps 4921524A02Rik, anticorps AI507642, anticorps AU021743, anticorps AW551584, anticorps C430041B13Rik, anticorps Lims1l, anticorps LIM zinc finger domain containing 1, anticorps LIM and senescent cell antigen-like domains 1, anticorps LIMS1, anticorps Lims1
- Sujet
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The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: PINCH, PINCH1
Protein Interaction Partner: RSU1, UBC, SUMO1, NEDD8, ILK, STUB1, MAPT, MBIP, Hoxa1, HNRNPU, STK11, PARVA, SMURF1, EHMT2, LPXN, NCK2, RBBP8, TMSB4X, TGFBR1, ACP6,
Protein Size: 387 - Poids moléculaire
- 44 kDa
- ID gène
- 3987
- NCBI Accession
- NM_001193485, NP_001180414
- UniProt
- B7Z7R3
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