RAP2A anticorps (C-Term)

N° du produit ABIN2789703

Détail du produit anti-RAP2A anticorps

Antigène: RAP2A (RAP2A, Member of RAS Oncogene Family (RAP2A))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Cheval, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Lapin, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAP2A est non-conjugé

Application: Western Blotting (WB)

Séquence: QIIRVKRYEK VPVILVGNKV DLESEREVSS SEGRALAEEW GCPFMETSAK

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%, Sheep: 93%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against RAP2A. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 183 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RAP2A

Antigène: RAP2A (RAP2A, Member of RAS Oncogene Family (RAP2A))

Autre désignation: RAP2A (RAP2A Produits)

Synonymes: anticorps krev, anticorps rap2, anticorps k-rev, anticorps rbbp-30, anticorps RAP2A, anticorps K-REV, anticorps KREV, anticorps RAP2, anticorps RbBP-30, anticorps 5830461H18Rik, anticorps RAP2A, member of RAS oncogene family, anticorps Rap2A GTPase, anticorps RAP2B, member of RAS oncogene family, anticorps RAS related protein 2a, anticorps RAP2A, anticorps Rap2a, anticorps rap2a, anticorps RAP2B

Sujet: RAP2A is a small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.
Alias Symbols: K-REV, KREV, RAP2, RbBP-30
Protein Interaction Partner: UBC, RPTOR, ELAVL1, RRP9, TM7SF2, PLG, SERPINA1, FTL, FKBP2, ENSA, EEF1A1, NEDD4, TNIK, RUNDC3A, GRIN1, RASIP1, RAPGEF5, RAPGEF6, ARHGAP29, RASSF5, MAP4K4, BMPR1B, GRIN2D, RGS14, RALGDS, SMAD1, TGFBR1, RAP2A, RAF1, MLLT4, FNTB, ACVR1, RAPGEF4, RAPGEF3, RA
Protein Size: 183

Poids moléculaire: 20 kDa

ID gène: 5911

NCBI Accession: NM_021033, NP_066361

UniProt: P10114