IL-19 anticorps (Middle Region)

N° du produit ABIN2789718

Détail du produit anti-IL-19 anticorps

Antigène: IL-19 (IL19) (Interleukin 19 (IL19))

Épitope: Middle Region

Reactivité: Humain, Rat, Chien, Boeuf (Vache), Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-19 est non-conjugé

Application: Western Blotting (WB)

Séquence: ILSTLETLQI IKPLDVCCVT KNLLAFYVDR VFKDHQEPNP KILRKISSIA

Homologie: Cow: 79%, Dog: 86%, Human: 100%, Rabbit: 79%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against IL19. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 215 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IL-19

Antigène: IL-19 (IL19) (Interleukin 19 (IL19))

Autre désignation: IL19 (IL19 Produits)

Synonymes: anticorps IL-10C, anticorps MDA1, anticorps NG.1, anticorps ZMDA1, anticorps IL19, anticorps interleukin 19, anticorps IL19, anticorps Il19

Sujet: The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.
Alias Symbols: IL-10C, MDA1, NG.1, ZMDA1
Protein Interaction Partner: IL20RA,
Protein Size: 215

Poids moléculaire: 18 kDa

ID gène: 29949

NCBI Accession: NM_153758, NP_715639

UniProt: Q5VUT3