CDK2AP1 anticorps (C-Term)
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- Antigène Voir toutes CDK2AP1 Anticorps
- CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CDK2AP1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LLAIIEELGK EIRPTYAGSK SAMERLKRGI IHARGLVREC LAETERNARS
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
- Attributs du produit
- This is a rabbit polyclonal antibody against CDK2AP1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CDK2AP1
- Top Product
- Discover our top product CDK2AP1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 115 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))
- Autre désignation
- CDK2AP1 (CDK2AP1 Produits)
- Synonymes
- anticorps MGC64532, anticorps doc1, anticorps st19, anticorps doc-1, anticorps dorc1, anticorps p12doc-1, anticorps Apc10, anticorps Cdkap1, anticorps DORC1, anticorps Doc1, anticorps ST19, anticorps p12, anticorps DOC1, anticorps p12DOC-1, anticorps cyclin-dependent kinase 2 associated protein 1 S homeolog, anticorps cyclin dependent kinase 2 associated protein 1, anticorps cyclin dependent kinase 2 associated protein 1 pseudogene, anticorps cyclin-dependent kinase 2 associated protein 1, anticorps CDK2 (cyclin-dependent kinase 2)-associated protein 1, anticorps cdk2ap1.S, anticorps CDK2AP1, anticorps LOC475806, anticorps cdk2ap1, anticorps Cdk2ap1
- Sujet
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The protein encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes.
Alias Symbols: DOC1, DORC1, ST19, doc-1, p12DOC-1
Protein Interaction Partner: MRFAP1L1, CCDC136, HDAC2, HDAC1, ZNF420, MTA3, VCP, CDK2AP2, Cebpb, HHV8GK18_gp81, ELAVL1, MBD3, MBD2, RBBP7, RBBP4, SRRM2, POLA1, CDK2, IGHA2, IGHA1, AMY1A,
Protein Size: 115 - Poids moléculaire
- 12 kDa
- ID gène
- 8099
- NCBI Accession
- NM_004642, NP_004633
- UniProt
- O14519
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