GPR68 anticorps (Middle Region)
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- Antigène Voir toutes GPR68 Anticorps
- GPR68 (G Protein-Coupled Receptor 68 (GPR68))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Cheval, Lapin, Chien, Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GPR68 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- SIYFLMHEEV IEDENQHRVC FEHYPIQAWQ RAINYYRFLV GFLFPICLLL
- Homologie
- Dog: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 79%, Rat: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against GPR68. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of Human GPR68
- Top Product
- Discover our top product GPR68 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 365 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- GPR68 (G Protein-Coupled Receptor 68 (GPR68))
- Autre désignation
- GPR68 (GPR68 Produits)
- Synonymes
- anticorps GPR68, anticorps GPR12A, anticorps OGR1, anticorps BB131428, anticorps Ogr1, anticorps G protein-coupled receptor 68, anticorps GPR68, anticorps LOC100348269, anticorps Gpr68
- Sujet
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Proton-sensing receptor is involved in pH homeostasis. GPR68 may represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. GPR68 mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca2+ mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer.
Alias Symbols: MGC111379, MGC156983, OGR1, GPR12A
Protein Size: 365 - Poids moléculaire
- 41 kDa
- ID gène
- 8111
- NCBI Accession
- NM_003485, NP_003476
- UniProt
- Q15743
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