FLNC anticorps (N-Term)
-
- Antigène Voir toutes FLNC Anticorps
- FLNC (Filamin C, gamma (FLNC))
-
Épitope
- N-Term
-
Reactivité
- Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp FLNC est non-conjugé
-
Application
- Western Blotting (WB)
- Séquence
- VGKSADFVVE AIGTEVGTLG FSIEGPSQAK IECDDKGDGS CDVRYWPTEP
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against FLNC. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human FLNC
- Top Product
- Discover our top product FLNC Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 2692 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy." dans: JACC. Basic to translational science, Vol. 1, Issue 5, pp. 344-359, (2016) (PubMed).
: "
-
FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy." dans: JACC. Basic to translational science, Vol. 1, Issue 5, pp. 344-359, (2016) (PubMed).
-
- Antigène
- FLNC (Filamin C, gamma (FLNC))
- Autre désignation
- FLNC (FLNC Produits)
- Sujet
-
This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ABP-280, ABP280A, ABPA, ABPL, FLJ10186, FLN2
Protein Interaction Partner: RAPGEF2, TRIM63, TRIM55, XIRP1, XIRP2, SYNPO2, UBC, KCMF1, CTTNBP2NL, ANKRD28, ARFGEF2, NCAPD2, TXNL1, PSMD13, PSMD12, PSMD3, NUP88, IKBKB, FLNB, AP3S1, NPM1, IGSF8, FN1, IQCB1, TP63, VCAM1, RPS6KA2, DYNLRB1, NUP133, SAP30BP, SF3A3, SRSF9, ENO1, EEF1G, EE
Protein Size: 2692 - Poids moléculaire
- 296 kDa
- ID gène
- 2318
- NCBI Accession
- NM_001127487, NP_001120959
- UniProt
- Q14315
-