CYFIP1 anticorps (C-Term)
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- Antigène Voir toutes CYFIP1 Anticorps
- CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cheval, Lapin, Cobaye, Chévre
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CYFIP1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- WAGCMIIVLL GQQRRFAVLD FCYHLLKVQK HDGKDEIIKN VPLKKMVERI
- Homologie
- Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against CYFIP1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CYFIP1
- Top Product
- Discover our top product CYFIP1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 1253 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))
- Autre désignation
- CYFIP1 (CYFIP1 Produits)
- Synonymes
- anticorps TUBGCP5, anticorps P140SRA-1, anticorps SHYC, anticorps SRA1, anticorps E030028J09Rik, anticorps P140sra1, anticorps Shyc, anticorps Sra-1, anticorps Sra1, anticorps l(7)1Rl, anticorps l71Rl, anticorps l7Rl1, anticorps mKIAA0068, anticorps pl-1, anticorps CY, anticorps CYFIP, anticorps fb15a06, anticorps wu:fb15a06, anticorps cytoplasmic FMR1 interacting protein 1, anticorps CYFIP1, anticorps cyfip1, anticorps Cyfip1
- Sujet
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CYFIP1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. CYFIP1 promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA By similarity. CYFIP1 regulates formation of membrane ruffles and lamellipodia. CYFIP1 plays a role in axon outgrowth. CYFIP1 binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. CYFIP1 may act as an invasion suppressor in cancers.
Alias Symbols: FLJ45151, P140SRA-1, SHYC, SRA1
Protein Interaction Partner: EFHC2, SUMO2, MEOX1, UBC, WWOX, PRPF40A, CLUH, TCERG1, NCKAP1, ARHGEF1, GAS7, APBB1, HECW2, RFX6, EFTUD2, SCTR, PPP1CC, GNB1, UBD, MARK4, YWHAZ, YWHAH, RYK, TERF2, TERF1, CYFIP1, RAC1, FMR1, ACTA1, FXR2, FXR1, NCL,
Protein Size: 1253 - Poids moléculaire
- 145 kDa
- ID gène
- 23191
- NCBI Accession
- NM_014608, NP_055423
- UniProt
- Q7L576
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