CRYGA anticorps (N-Term)

N° du produit ABIN2790019

Détail du produit anti-CRYGA anticorps

Antigène: CRYGA (Crystallin, gamma A (CRYGA))

Épitope: N-Term

Reactivité: Humain, Souris, Lapin, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRYGA est non-conjugé

Application: Western Blotting (WB)

Séquence: SIRVDSGCWM LYERPNYQGH QYFLRRGKYP DYQHWMGLSD SVQSCRIIPH

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 79%, Zebrafish: 82%

Attributs du produit: This is a rabbit polyclonal antibody against CRYGA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CRYGA

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 174 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CRYGA

Antigène: CRYGA (Crystallin, gamma A (CRYGA))

Autre désignation: CRYGA (CRYGA Produits)

Synonymes: anticorps CRY-g-A, anticorps CRYG1, anticorps CRYG5, anticorps Cryg-4, anticorps DGcry-4, anticorps cryg1, anticorps cryg5, anticorps MGC85425, anticorps CRYGA, anticorps crystallin gamma A, anticorps crystallin, gamma A, anticorps crystallin gamma A L homeolog, anticorps gamma-crystallin A, anticorps CRYGA, anticorps Cryga, anticorps cryga.L, anticorps LOC100630282, anticorps LOC100355936

Sujet: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.
Alias Symbols: CRY-g-A, CRYG1, CRYG5
Protein Interaction Partner: TRAF1,
Protein Size: 174

Poids moléculaire: 21 kDa

ID gène: 1418

NCBI Accession: NM_014617, NP_055432

UniProt: P11844