REPS2 anticorps (C-Term)

N° du produit ABIN2790025

Détail du produit anti-REPS2 anticorps

Antigène: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Épitope: C-Term

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Porc, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp REPS2 est non-conjugé

Application: Western Blotting (WB)

Séquence: KDVLYSQPPS KPIRRKFRPE NQATENQEPS TAASGPASAA TMKPHPTVQK

Homologie: Cow: 100%, Dog: 80%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 83%, Pig: 100%, Rabbit: 93%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against REPS2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human REPS2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur REPS2

Antigène: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Autre désignation: REPS2 (REPS2 Produits)

Synonymes: anticorps POB1, anticorps RALBP1 associated Eps domain containing 2, anticorps RALBP1 associated Eps domain containing protein 2, anticorps REPS2, anticorps Reps2

Sujet: The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: EPN1, CDK1, AP2A1, GRB2, AMPH, AR, CDK5RAP2, REPS1, RALBP1, EPS15, ASAP1, ASAP2, PXN, RALB, RELA,
Protein Size: 521

Poids moléculaire: 57 kDa

ID gène: 9185

Pathways: EGFR Signaling Pathway