C8orf4 anticorps (N-Term)
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- Antigène Voir toutes C8orf4 Anticorps
- C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))
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Épitope
- N-Term
- Reactivité
- Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp C8orf4 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- TASRKKAVGN IFENTDQESL ERLFRNSGDK KAEERAKIIF AIDQDVEEKT
- Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against C8orf4. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human C8orf4
- Top Product
- Discover our top product C8orf4 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 106 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))
- Autre désignation
- C8orf4 (C8orf4 Produits)
- Synonymes
- anticorps TC-1, anticorps TC1, anticorps 1110065B09Rik, anticorps AW121743, anticorps AW321058, anticorps C8ORF4, anticorps transcriptional and immune response regulator, anticorps chromosome 22 open reading frame, human C8orf4, anticorps TCIM, anticorps C22H8ORF4, anticorps Tcim
- Sujet
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This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.
Alias Symbols: MGC22806, TC-1, TC1, hTC-1
Protein Interaction Partner: ELAVL1, UBC,
Protein Size: 106 - Poids moléculaire
- 12 kDa
- ID gène
- 56892
- NCBI Accession
- NM_020130, NP_064515
- UniProt
- Q9NR00
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